US Open: Potapova vs Anisimova Odds, Picks & Live Streaming
Power tennis will take center stage in New York on Saturday, September 5, when Anastasia Potapova faces Amanda Anisimova in the US Open third round. Both women can seize control with one clean return game, making this a dangerous matchup for anyone expecting the favorite to cruise without resistance.
Anisimova owns the heavier first-strike game and a 17-5 hard-court record this season. Potapova brings legitimate upset credentials, including 2026 victories over Coco Gauff and Elena Rybakina. The American deserves favorite status—but she will need to earn it.
Building a weekend betting card? Use our tennis betting guide to compare spreads, totals, and set markets before wagering.
Potapova vs Anisimova Betting Odds
| Betting Market | Reference Line | Place Bet! |
|---|---|---|
| Anastasia Potapova ML | +365 | Place Bet @ BetMGM |
| Amanda Anisimova ML | -325 | Place Bet @ BetMGM |
| O/U | 22.5 Games | +155 | -192 | Place Bet @ BetMGM |
Expert Picks: Potapova vs Anisimova
🥇 Best Bet: Amanda Anisimova -4.5 Games
Anisimova’s moneyline carries little standalone value, but the game spread offers a more playable price. Her early ball-striking should pressure Potapova’s second serve, while her own first serve creates shorter holds. If the American limits the loose service games that appeared against Lilli Tagger, she can build separation across two sets.
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Pick 2: Amanda Anisimova to Win 2-0
Potapova has the shot-making ability to keep either set competitive, but Anisimova has been the more dependable hard-court player. She responded to losing the second set against Tagger by dominating the decider 6-1. That ability to reset quickly should help her avoid allowing one poor stretch to become an entire lost set.
Pick 3: Under 21.5 Total Games
A straight-sets Anisimova victory creates several paths under this number: 6-4, 6-3; 6-3, 6-4; or anything more comfortable. Potapova must consistently protect her second serve to extend both sets. Anisimova’s aggressive return position should make that difficult, particularly once she begins timing Potapova’s delivery.
Pick 4: Anastasia Potapova Under 9.5 Total Games
This selection leaves room for Potapova to push one set deep without requiring a complete blowout. Anisimova has the pace to break from neutral positions and should generate repeated opportunities whenever Potapova misses her first serve. A projected 6-4, 6-3 result keeps the underdog comfortably beneath the number.
Potapova vs Anisimova Matchup Comparison
| Category | Anastasia Potapova | Amanda Anisimova |
|---|---|---|
| WTA Ranking | No. 25 | No. 10 |
| Age | 25 | 25 |
| Height | 5’9” | 5’11” |
| 2026 Singles Record | 27-19 | 22-11 |
| 2026 Hard-Court Record | — | 17-5 |
| US Open First Round | Beat Semenistaja 6-2, 6-2 | Beat Krueger 6-1, 6-3 |
| US Open Second Round | Beat Jeanjean 6-4, 2-6, 6-3 | Beat Tagger 6-3, 3-6, 6-1 |
| Singles Head-to-Head | 0 | 1 |
Key Betting Trends
- Anisimova is 17-5 across her first 22 hard-court matches of 2026.
- She reached the US Open final in 2025.
- Anisimova has won four of her previous five completed matches.
- She struck seven aces against Tagger in the second round.
- Anisimova won 76% of her first-serve points in that victory.
- She has dropped one set through two US Open matches.
- Potapova is 27-19 this season.
- Potapova has also dropped one set during the tournament.
- She defeated Gauff at the French Open and Rybakina in Madrid this season.
- Anisimova leads the singles head-to-head 1-0.
- Their previous meeting was played on clay seven years ago.
Where to Watch Potapova vs Anisimova in the US
- Date: Saturday, September 5, 2026
- Round: Third Round/Round of 32
- Venue: USTA Billie Jean King National Tennis Center
- Location: Flushing Meadows, Queens, New York
- TV: ESPN or ESPN2, subject to court assignment
- Streaming: ESPN App and ESPN Unlimited
- Spanish-language coverage: ESPN Deportes
Final Prediction: Will Anisimova Survive Potapova’s Upset Threat?
Potapova is capable of making this uncomfortable. She owns the variety, pace, and competitive edge to challenge Anisimova early, particularly if the American’s second serve remains vulnerable.
The longer view still favors the No. 10 player. Anisimova has been excellent on hard courts, possesses the heavier return and has already shown that she can reset after losing momentum. Potapova may stay within one break through the opening set, but Anisimova’s relentless baseline pressure should create greater separation as the match develops. Expect flashes of high-level shot-making from both women—and more control from the American when the biggest points arrive.
- Prediction: Amanda Anisimova wins 6-4, 6-3
- Best Bet: Amanda Anisimova -4.5 Games
- Set Pick: Amanda Anisimova to Win 2-0
- Totals Play: Under 21.5 Games
- Player Total: Anastasia Potapova Under 9.5 Games
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