US Open: Zverev vs Khachanov Odds, Picks & How to Watch
Friday afternoon in New York brings a rematch with Olympic history and a ranking gap that tells only half the story. Alexander Zverev faces Karen Khachanov on September 11, one victory from returning to the US Open final. The top seed arrives after dismantling Botic van de Zandschulp in straight sets. Khachanov, ranked No. 50, has already eliminated two seeded opponents and carries the freshest legs after Alexander Blockx retired during their quarterfinal.
Zverev leads the rivalry 6-3. Khachanov won the latest meeting. For bettors, the question is whether his serve can keep the favorite uncomfortable long enough to threaten another upset.
Building your Friday card? Compare more expert tennis betting picks before wagering on the US Open semifinals.
Zverev vs Khachanov Betting Odds
| Betting Market | Reference Line | Place Bet! |
|---|---|---|
| Alexander Zverev ML | -500 | Place Bet @ BetMGM |
| Karen Khachanov ML | +350 | Place Bet @ BetMGM |
| O/U | 38.5 Games | -120 | -120 | Place Bet @ BetMGM |

Expert Picks: Alexander Zverev vs Karen Khachanov
🥇 Best Bet: Alexander Zverev -5.5 Games
Zverev can create separation without producing a flawless serving day. His backhand is sturdier, his return position handles Khachanov’s pace, and he has won six of nine meetings. Khachanov may keep two sets competitive, but the favorite’s superior movement and second-serve pressure should produce at least one lopsided set and a cover.
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Pick 2: First Set Over 9.5 Games
Neither player wants to expose his second serve before settling into the semifinal. Zverev should begin behind heavy first deliveries, while Khachanov’s fastest path to scoreboard pressure is protecting his own service games. With both likely feeling out baseline patterns early, ten opening-set games offer a reachable target.
Pick 3: Alexander Zverev to Win 3-1
Khachanov is too dangerous to treat as a routine semifinal opponent. He beat Zverev in Toronto last season and has already removed Felix Auger-Aliassime and Learner Tien in New York. Still, sustaining four clean sets against Zverev’s backhand looks unlikely. One stolen set feels more realistic than a first major final.
Pick 4: Tiebreak to Be Played
These are two of the tallest, heaviest servers left in the draw, and their previous hard-court meeting ended with a deciding-set tiebreak. Khachanov has enough first-strike power to force at least one set beyond twelve games. Zverev’s occasional double-fault clusters also create the uneven service rhythm that can lead to a breaker.
Zverev vs Khachanov Matchup Comparison

| Category | Zverev | Khachanov |
|---|---|---|
| ATP ranking | No. 2 | No. 50 |
| Age | 29 | 30 |
| Height | 6’6” | 6’6” |
| Grand Slam titles | 1 | 0 |
| Best US Open result | Finalist, 2020 | Semifinalist, 2022 |
| 2026 US Open result | Semifinal | Semifinal |
| Head-to-head wins | 6 | 3 |
| Quarterfinal result | Won in straight sets | Advanced by retirement |
Zverev vs Khachanov Head-to-Head
Zverev leads the overall series 6-3, but Khachanov took their most recent meeting.
| Notable Meeting | Winner | Score |
|---|---|---|
| 2021 Tokyo Olympic Final | Alexander Zverev | 6-3, 6-1 |
| 2025 Toronto Semifinal | Karen Khachanov | 6-3, 4-6, 7-6(4) |
Key Betting Trends
- Zverev leads the career series 6-3.
- Khachanov won their latest meeting in three sets.
- Four of their nine meetings have required a deciding set.
- Zverev defeated Khachanov in the 2021 Olympic gold-medal match.
- Zverev has reached the semifinals at all four majors in 2026.
- He has won his last six US Open sets.
- Zverev conceded only eight games against Van de Zandschulp.
- Khachanov has defeated two seeded opponents during this tournament.
- Khachanov needed five sets to eliminate Learner Tien.
- His quarterfinal ended after only one hour and 38 minutes.
- Zverev committed five double faults in his quarterfinal.
- Khachanov is appearing in his third career Grand Slam semifinal.
Where to Watch Zverev vs Khachanov in the US
- Date: Friday, September 11, 2026
- Round: Men’s singles semifinal
- Venue: Arthur Ashe Stadium
- Location: Flushing Meadows, Queens, New York
- TV: ESPN
- Streaming: ESPN App and ESPN Unlimited
- Spanish-language coverage: ESPN Deportes

Final Prediction: Will Zverev Return to the US Open Final?
Khachanov owns enough power—and enough belief after beating Zverev in Toronto—to make the opening stages uncomfortable. His shorter quarterfinal also removes the fatigue concern created by the five-set escape against Tien.
The matchup still tilts toward Zverev. His backhand is the safest groundstroke on the court, his defensive range is superior, and his return should expose Khachanov whenever the first serve disappears. Expect one extended set to fall to the underdog, probably through a tiebreak. Once rallies lengthen, Zverev should take command and pull away late at Arthur Ashe.
- Prediction: Zverev wins in four sets, 6-4, 6-7, 6-3, 6-2.
- Best Bet: Alexander Zverev -5.5 Games
- Opening-Set Pick: Over 9.5 Games
- Match Prop: Tiebreak to Be Played
- Correct Score: Alexander Zverev 3-1
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