New Orleans Saints @ Seattle Seahawks 09/21/2025
A late-afternoon kickoff at Lumen Field with the 12s in full voice? That’s a September Sunday in Seattle that always feels bigger than the standings might suggest in Week 3. The Seahawks sit at 1-1, fresh off a 31-17 road win in Pittsburgh that steadied the ship after an opening home loss. Through two games, Seattle’s averaging 22.0 points per game while allowing 17.0, a tidy early-season profile that fits a defense-first identity under new head coach Mike Macdonald. On the other side, the New Orleans Saints come in at 0-2 after a tight 26-21 home loss to the 49ers. Through two, the Saints are averaging 17.0 points per game and giving up 23.0—close, competitive, but not closing.
This one matters for both sides, and bettors will care just as much. New Orleans has had Seattle’s number lately—four wins in the last five meetings, including a 39-32 shootout the last time they met. But Seattle’s known for the home-field edge, and even at 0-1 in the building so far, Lumen Field tilts the board toward the hosts. With the early-season data in hand, a totals angle looks intriguing given Seattle’s 22.0 per game and New Orleans’ 17.0, plus the Seahawks’ recent uptick on offense. Week 3 is where teams begin to show who they really are—and where edges emerge.
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Our betting predictions for the match New Orleans Saints @ Seattle Seahawks
Main Tip: Totals Over/Under – Over 41.0 Points
Our primary betting prediction is Over 41.0 points at around -125 at Caesars Sportsbook. Seattle’s early profile—22.0 points scored and 17.0 allowed on average—suggests efficiency on both sides, but their offense found rhythm in Pittsburgh. The Saints, despite the 0-2 start, moved the ball late against San Francisco and have the weapons to contribute. Factor in a recent high-scoring head-to-head (39-32), and you can see a script that edges past 41 with a mix of chunk plays and red-zone conversions.
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Tip 2: Moneyline – Seattle Seahawks
Our second betting tip is Seahawks Moneyline at bet365 at very competitive odds. Lumen Field, even after an opening stumble, is a difficult ask for a visiting team still trying to iron out late-game execution. Seattle’s defense under Mike Macdonald looks organized and opportunistic; its offense is balanced enough to avoid long scoring droughts. New Orleans can punch back, but with the Saints still chasing their first win, the home side is the more reliable anchor for parlays or a straight Moneyline stake.
Tip 3: New Orleans Saints +8.0 Spread
Our final prediction is New Orleans Saints +8.0 at about -125 at bet365. That might feel counterintuitive next to the Seahawks Moneyline, but it’s a common NFL betting reality—home favorite wins while the road dog sneaks in the cover. The Saints have hung around in both games, averaging 17.0 points while holding opponents to 23.0. Their defense is sturdy enough to slow Seattle’s run game and force longer fields. Expect a one-score game late, giving the +8.0 a live path even if Seattle closes it out.
Team news
Both teams enter with early-season urgency. For Seattle, Mike Macdonald is installing a defense built on disguise and leverage, and you saw more of that in the win at Pittsburgh. Offensively, the veteran quarterback play and a deep wide receiver room keep them multiple; if the ground game sets up play-action, they’re tough at home.
New Orleans under Kellen Moore remains defense-first, with a secondary that usually travels well and a front capable of squeezing edges in the run game. The offense is still searching for a full four-quarter output, but the skill talent is there to pop—especially if they can keep the chains moving on early downs and avoid long third-and-longs in the noise at Lumen.
Seattle Seahawks performance check
Seattle’s 1-1 start includes a 0-1 home mark and a decisive 31-17 road win over the Steelers. The arithmetic says 22.0 points per game for, 17.0 against—solid margins that reflect a defense settling in. Macdonald’s group mixes simulated pressure and tight zone drops to take away easy throws, and when they tackle well, the explosives dry up. The turnover profile is trending in the right direction, too; they created key momentum swings in Pittsburgh and looked faster on the second level.
On offense, Seattle feels balanced. The pass game features an experienced quarterback distributing to multiple targets, leveraging intermediate crossers and sideline comebacks. The run game doesn’t have to dominate; it just needs to stay on schedule and protect the QB from predictable pass-rush downs. In front of the home crowd, cadence and tempo become their allies. The key for Seattle will be finishing drives—field goals won’t beat quality teams long-term, and New Orleans’ defense can force those if you bog down in the low red zone. But given the current averages and the Week 2 uptick, the Seahawks look ready to post another low- to mid-20s output with upside if the explosives hit.
How is the current performance of the New Orleans Saints
At 0-2, Kellen Moore’s Saints are playing competitive football without the payoff late. They’re averaging 17.0 points per game and allowing 23.0, which tells you they’re close—one or two high-leverage plays shy in both weeks. Offensively, the plan is clear: protect the ball, use the short game, and take selective shots to a gifted receiving corps. A strong day from the backs in the screen game would help quiet the pass rush and set up manageable third downs.
Defensively, New Orleans typically travels well. They play sound coverage, rally to the ball, and force opponents to stack first downs rather than hunt home runs. That style can keep a road game tight, even in a hostile environment. The 26-21 setback to San Francisco showed resilience—multiple scoring drives, a defense that made the Niners earn it, and a team that didn’t fold when the script got tough. The challenge now is clearing the final hurdle: red-zone conversions and two-minute execution. If they unlock just a bit more on offense, the +8.0 looks very live.
Statistics
– Last direct match: New Orleans beat Seattle 39-32 at home in a high-tempo game that opened up after halftime, showcasing explosive plays and quick-strike drives.
- Head-to-Head last five meetings: Seattle 1 win, New Orleans 4 wins. The Saints have consistently found ways to create mismatches and finish late in these spots.
- Performance last five matches (all competitions):
- Seattle Seahawks: 2 wins, 2 losses. Trending up after the Pittsburgh result, with the defense allowing just 17.0 per game this season.
- New Orleans Saints: 0 wins, 4 losses. The margins are narrowing, and the offense showed better rhythm against San Francisco.
- Last match results:
- Seattle Seahawks: 31-17 away win over the Pittsburgh Steelers—efficient on offense, opportunistic on defense.
- New Orleans Saints: 21-26 home loss to the San Francisco 49ers—competitive throughout, but couldn’t quite close.
- 2025 early-season averages:
- Seattle: 22.0 points for, 17.0 against.
- New Orleans: 17.0 points for, 23.0 against.
- Division context:
- Seattle competes in the NFC West, a physical division where every inch matters. This is a chance to bank a cross-conference-style performance against an NFC South visitor at a critical early-season juncture.
- New Orleans battles in the NFC South, where early wins stabilize the season. A competitive road showing here keeps them firmly in the mix with 15 games still ahead in a 17-game slate.
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TrustnBet Final Thoughts
Here’s how we get there. First tip: Over 41.0 taps into Seattle’s rising offensive comfort and New Orleans’ ability to punch back, especially off scripted drives and quick hitters that travel well. Second tip: Seahawks Moneyline leans into home-field advantage and the steadier baseline under Mike Macdonald. Third tip: Saints +8.0 acknowledges the tight-game tendencies and the Saints’ defense keeping this within one score late. That’s the parlay of logic: Over for pace, Seattle to win at home, Saints to cover a generous number.
