CF Monterrey vs Santos Laguna Predictions & Odds - Liga MX Picks

Our soccer betting prediction for the Liga MX opener between CF Monterrey and Santos Laguna takes center stage this Saturday, July 18, 2026, at Estadio BBVA. Both teams are eager to kick off the 2026 Apertura season on a high note. CF Monterrey, managed by Matías Almeyda, looks to leverage their home advantage and improve on their recent performances. Meanwhile, Santos Laguna, guided by coach Renato Paiva, hopes to overcome their travel woes and challenge Monterrey’s dominance. The two sides last met in a match that saw Santos securing a 3-0 victory at home, but Monterrey will be keen to flip the script at their fortress. According to recent statistics, Monterrey averages 1.92 goals per match and has a strong home record against Santos. On the other hand, Santos Laguna averages just 0.88 goals scored per match, struggling particularly in away games. With these factors in mind, we anticipate an intriguing encounter for soccer betting enthusiasts.

Our 3 Betting Predictions for CF Monterrey vs Santos Laguna

1. CF Monterrey to Win

Given Monterrey's strong home form and historical edge over Santos Laguna, they are favored to emerge victorious in this clash. BetMGM Sportsbook offers the best odds at -189 for a Monterrey win. With key players like Berterame and Ocampos in form, Monterrey is well-positioned to capitalize on their attacking prowess and secure three points. This prediction aligns with the home advantage and Santos’ poor traveling record.

2. Both Teams to Score

Despite Santos Laguna’s struggles on the road, their recent offensive improvements suggest they might find the net. FanDuel Sportsbook has the best odds for both teams to score at -189. Monterrey has shown some defensive vulnerabilities, and with Santos eager to start the season strong, this market presents value. The odds and recent form point towards a competitive match with goals from both sides.

3. Over 3.5 Goals

With Monterrey averaging 1.92 goals per game and Santos’ defensive frailties, the over 3.5 goals market offers intriguing value. FanDuel Sportsbook provides odds of +100 for this outcome. Both teams have shown potential for high-scoring games, and given the last direct meeting ended 3-0, this match could see plenty of goal-mouth action.

Further Predictions

Team Statistics

CF Monterrey - Current Form

Monterrey enters this match with a mixed bag of recent results, having registered 1 win, 1 tie, and 3 losses in their last five encounters. Their last outing was a 0-3 away loss against Santos Laguna. Despite this, Monterrey's home form has been solid, and with Matías Almeyda at the helm, they aim to rectify their previous shortcomings. Historically, Monterrey has won 52% of their matches, making them formidable contenders at home.

Santos Laguna - Current Form

Santos Laguna, with a similar recent form to Monterrey, boasts 1 win, 1 tie, and 3 losses in their last five games. Their most recent match was a 3-0 home victory over Monterrey, which they'll look to replicate. However, their away record remains a concern, as they have struggled to find consistency on the road, contributing significantly to their overall win percentage of just 23.5% from previous seasons.

Latest Odds Boosts

Ousmane Dembele & Mikel Oyarzabal Each Score Goal in 90 Minutes on 7/14 +950

Ends in

Expired

Must be 21 or older to gamble. Know When To Stop Before You Start®.Gambling Problem? Call or Text 1-800-GAMBLER Caesars Sportsbook is committed to supporting Responsible Gaming.

France 2+ Goals in 90 Minutes & Michael Olise 1+ Assists on 7/14 +400

Ends in

Expired

Must be 21 or older to gamble. Know When To Stop Before You Start®.Gambling Problem? Call or Text 1-800-GAMBLER Caesars Sportsbook is committed to supporting Responsible Gaming.

Keyplayer Statistics/Momentum/External Factors

Lucas Ocampos stands out for CF Monterrey, having contributed significantly to their attacking prowess with 5 goals and 6 assists last season. His ability to create and finish chances makes him a key threat. For Santos Laguna, Bruno Barticciotto provides a spark with his scoring ability, netting 6 goals in 10 matches last season. The absence of Anthony Lozano due to suspension could impact Santos' attacking options, placing more pressure on Barticciotto to deliver in this crucial opener.

Last Direct Match

The last meeting between CF Monterrey and Santos Laguna ended in a 3-0 home victory for Santos Laguna, highlighting their capability to challenge Monterrey, although the dynamics may differ away from home.

Performance Last 5 Matches

Both teams share a similar recent record with 1 win, 1 tie, and 3 losses in their last five matches, indicating no clear momentum advantage.

Performance

CF Monterrey

Last games

CF Monterrey performance of the last 6 home matches

Victories

33%

Over 2.5

100%

Santos Laguna

Last games

Santos Laguna performance of the last 4 away matches

Victories

25%

Over 2.5

75%

TrustnBet Predictions Summary

Our three betting tips for this match are shaped by Monterrey's home advantage and historical dominance over Santos Laguna. The recommended bet for a Monterrey win at -189 reflects their superior home form and squad depth. The expectation for both teams to score, priced at -189, considers Santos’ potential to find the net despite away struggles. Lastly, the over 3.5 goals market at +100 offers value given both sides' attacking potential and recent high-scoring encounters.